- Longvida Optimized Curcumin
- Crosses Blood-Brain Barrier
- Free Form Curcumin with Superior Bioavailability
- A Dietary Supplement
Curcumin is a powerful free radical neutralizer that is known to support balanced immune function, but is also known to have poor bioavailability. NOW CurcuBrain features Longvida Optimized Curcumin, which in studies exhibits up to 65 times the bioavailability of free curcuminoids compared with generic curcumin. Longvida is absorbed by the GI tract and delivered to the rest of the body as free curcumin, the active form in the body. Longvida is shown to penetrate the blood-brain barrier for the support of healthy neuronal tissues.
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OUTSTANDINGTHE ABSOLUTE BEST CURCUMIN ON THE MARKET. It crosses the blood brain barrier and is a patented brand. I used to use BCM-95 but this is superior.
Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population
Katherine HM Cox
Andrew B Scholey
Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, VIC, Australia
Andrew B Scholey, Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, VIC, 3122, Australia. Email: [email protected]
Curcumin possesses many properties which may prevent or ameliorate pathological processes underlying age-related cognitive decline, dementia or mood disorders. These benefits in preclinical studies have not been established in humans. This randomized, double-blind, placebo-controlled trial examined the acute (1 and 3 h after a single dose), chronic (4 weeks) and acute-on-chronic (1 and 3 h after single dose following chronic treatment) effects of solid lipid curcumin formulation (400 mg as Longvida®) on cognitive function, mood and blood biomarkers in 60 healthy adults aged 60–85. One hour after administration curcumin significantly improved performance on sustained attention and working memory tasks, compared with placebo. Working memory and mood (general fatigue and change in state calmness, contentedness and fatigue induced by psychological stress) were significantly better following chronic treatment. A significant acute-on-chronic treatment effect on alertness and contentedness was also observed. Curcumin was associated with significantly reduced total and LDL cholesterol and had no effect on hematological safety measures. To our knowledge this is the first study to examine the effects of curcumin on cognition and mood in a healthy older population or to examine any acute behavioral effects in humans. Results highlight the need for further investigation of the potential psychological and cognitive benefits of curcumin in an older population.