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Pyruvate is a 3-carbon compound formed from the glycolytic breakdown of glucose or glycogen. It can be reduced to lactate in the cytoplasm or oxidatively decarboxylated to acetyl CoA in the mitochondrion; in other words, it is the product of sugar metabolism. Once formed, pyruvate initiates the Kreb's cycle. The Kreb's cycle is an energy cycle that manages the production and formation of ATP (energy). Pyruvate has been acknowledged for is potential role in improving endurance during aerobic activities, reducing body fat, reducing fatigue, lowering blood lipids, increasing energy production (ATP), and decreasing the possibility of regaining previously lost fat mass.
Supplemental pyruvate may actually boost metabolism and energy levels by increasing the amount of ATP in the body. ATP provides energy to the mitochondria which fuels every cell in the body; more ATP may potentially make the mitochondria burn faster, which has been suggested to decrease the store of body fat. Pyruvate has also been suggested to increase glucose extraction, or the ability of muscle cells to pull glucose from the blood to be utilized as energy; the availability of glucose spares muscle glycogen. By making more energy available to the working muscles, pyruvate may play a beneficial role in extending endurance and improving performance in aerobic athletes.
When stacked with creatine, pyruvate has been shown to potentially increase power and strength, decrease body fat, and increase lean muscle mass. It has been noted that pyruvate and creatine together work better than either one alone. Pyruvate may also be stacked with dihydroxyacetone (DHA) to elicit beneficial effects on athletic performance. When taken together, pyruvate and DHA have been shown to increase muscle glycogen concentration, which may elicit a positive effect on fighting exhaustion in both upper and lower body endurance.
FDA: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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