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Endurox Endurox R4, 2.28 Lbs.

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Improve Performance 55% And Reduce Post-Exercise Muscle Stress By 36%!

Endurox R4 - Following Exercise

Endurox R4 Performance/Recovery Drink was developed by leading exercise physiologists and based on landmark research redefining how the exercising muscle recovers. Endurox R4 contains the patented 4 to1 ratio of carbohydrate to protein to speed muscle glycogen replenishment and rebuild muscle protein after exercise, antioxidants to reduce post-exercise muscle damage and glutamine to help reduce muscle stress.

In clinical studies against the leading sports drink was proven to enhance performance and extend endurance by 55% in a subsequent workout and decrease post-exercise muscle damage by 36%. Endurox R4 enables you to train harder and better the next day and everyday.

Product Profile

The introduction of Endurox R4 Performance/Recovery Drink begins a new chapter in how nutrition can enhance aerobic performance. In l997, leading exercise physiologists met in Colorado Springs, Colorado and developed a new model built on leading edge research that explains how the interaction of key physiological and nutritional factors enable muscles to operate at peak performance.

Endurox R4 is a technologically advanced sports drink based on this new model. In three clinical trials the researchers found, compared to Gatorade, Endurox R4:

Enhanced performance and extended endurance by 55%
Reduced free radical buildup by 69%
Increased muscle glycogen replenishment by 220%
Reduced post exercise muscle damage by 36%

The patented Endurox R4 formula includes electrolytes, high glycemic carbohydrates and whey protein in a 4:1 ratio (Optimal Recovery Ratio), arginine, antioxidant vitamins E and C, glutamine, branched chain amino acids and the natural herb, ciwujia. Endurox R4 is a total nutritional approach to muscle performance and recovery because it is specifically designed to:

Restore electrolytes and water.
Replenish glycogen stores rapidly.
Reduce muscle and oxidative stress.
Rebuild muscle protein.

The results of the clinical trials provide powerful support that Endurox R4, by improving muscle performance and enhancing recovery, should be the product of choice for any athlete engaged in aerobic activities such as running, biking or swimming or team sports such as basketball, football or soccer.

The R4 System

The R4 System is an important milestone in our understanding of exercise physiology and is the basis of a new book, Optimal Muscle Recovery by Dr. Edmund Burke (Avery Publishing). Based on leading edge science, the R4 System establishes a new model that explains how the interaction of key physiological and nutritional factors enable muscles to operate at peak levels. Equally important, the R4 System establishes four simple, practical principles that every aerobic athlete can incorporate into his/her daily training to optimize recovery and achieve full muscle potential.

To understand why the R4 System represents a major breakthrough, one must look at research in exercise physiology conducted over the last 30 years. The first important milestone was the finding in the late 60's that showed that fluid and electrolyte replenishment play an essential role in muscle performance before, during and after exercise. The second milestone, in the 70's, defined the role carbohydrate supplementation plays in extending endurance and speeding recovery. These studies led to the technique of carbohydrate loading.

In the 90's research conducted at leading universities has significantly advanced our understanding of muscle physiology and has identified additional factors that influence muscle performance. This research has shown that:

Insulin stimulates the replenishment of muscle glycogen stores and prevents protein breakdown
Insulin is so essential in the post exercise recovery process that it can be termed the "master recovery hormone"
Protein and specific amino acids can enhance the insulin response thereby speeding muscle recovery
Free radicals buildup (oxidative stress) is an important component of exercise induced muscle damage
Anti-oxidants, amino acids and certain natural supplements can help reduce muscle damage and prevent oxidative and muscle stress

These scientific findings coupled with previous research on hydration and carbohydrate utilization has led to a new model of exercise physiology - the R4 System. The R4 System is based on four core principles:

Restore electrolytes and water.
Replenish glycogen stores rapidly.
Reduce muscle and oxidative stress.
Rebuild muscle protein.

The R4 System provides simple framework for the aerobic athlete to optimize muscle performance and speed recovery.

Clinical Trials

Three trials were fielded to determine if a drink based on the R4 System would deliver these benefits. In the first trial conducted by Drs. Peter Raven and John Ivy, subjects were depleted of muscle glycogen, were provided either Endurox R4 Performance/Recovery Drink or Gatorade during recovery. Following the recovery phase subjects underwent a performance test measuring how long they could exercise at 85% VO2 max. In the second trial, conducted by Dr. John Seifert, subjects ran for 45 minutes, then consumed Gatorade or Endurox R4, bicycled for 45 minutes and then completed a performance trial. In the third trial conducted by Dr. John Ivy, subjects were depleted of muscle glycogen and a muscle biopsy was then taken. The subjects then consumed either Endurox R4 or Gatorade and a second muscle biosy 2 hours later was taken to measure glycogen levels.

The researchers found that Endurox R4 when compared to Gatorade:

Increased mean performance up to 66%
Reduced total free radical buildup by 69%
Stimulated insulin levels by 70%
Produced equivalent rates of rehydration
Decreased post exercise muscle damage by 36%
Increased muscle glycogen levels 2.2 fold

1. Effects Of Recovery Drinks After Prolonged Glycogen- Depletion Exercise

Williams, M., J. Ivy, And P. Raven. Cardiovascular Research Institute University of North Texas Health Science Center at Fort Worth, TX 76107 and Department of Kinesiology University of Texas, Austin, TX 78712

Purpose: Eight high-fit (bicycle VO2max = 62.4 (1.10 ml (kg -1(min-1) male cyclists, aged 28.4 (1.65 yrs. performed a two hour endurance bicycle exercise to achieve depletion of skeletal muscle and liver glycogen. During recovery, R4 Recovery Drink, or Gatorade, was ingested to investigate their relative restorative capacities to enable further exercise.

Methods: Each subject performed two days of resting: one for each drink presented in random order. On each testing day, the twelve-hour fasted subject performed a two-hour cycling exercise bout at 75% VO2max followed by one to three 5-minute sprints at 85% VO2max. At the end of this exercise blood glucose concentrations were 3.98 (0.138 mmol/L. A four-hour recovery period ensued in which the subject was given 24 ounces of the recovery drink. A performance test at 85% VO2max to exhaustion was then conducted. Ventilatory responses were collected breath-to-breath, while venous blood samples were measured for oxidation products, glucose and insulin concentrations.

Results: The recovery phase showed significant increases in both plasma glucose and insulin following R4 Recovery Drink ingestion as compared to Gatorade. There was a significant increase in time to exhaustion (+66%) following R4 Recovery Drink during the performance ride compared to Gatorade. Final oxidation products following R4 Recovery Drink ingestion were significantly decreased as compared to Gatorade ingestion, as well as Thiobarbituric Acid Reactive Substrates (T-BARS). Conclusions: These data indicate that recovery from glycogen-depleting exercise was significantly enhanced by R4 Recovery Drink when compared to Gatorade. In addition, R4 Recovery Drink decreased the formation of final oxidation products, when compared to Gatorade.

2.The Effect of Two Sports Drink Formulations on Muscle Stress and Performance

S.L. Ready, J.G. Seifert. & E. Burke. Human Performance Lab, SCSU, St. Cloud, MN 56303. Dept. of Biology, UCCS, Colorado Springs, CO.

Creatine kinase (CK) levels are frequently used as an indicator of muscle stress and damage. It is thought that CK leakage from cells occurs because of a disruption in the cell membrane. The purpose of this study was to compare two formulations on post-exercise muscle stress and performance time in a moderate-intensity duathlon. Ten college age males and females ingested a 15% CHO/protein/electrolyte beverage (CP) in a formulation containing CHO: protein in a 4:1 ratio or a 6% CHO/electrolyte (CE) beverage in a double blind, counterbalanced design. Subjects completed a 45-min run, rested in a 10-min transition, cycled for 90 min, and then performed a 90kJ time trial (TT). Each sport drink was ingested during the transition (360 ml) and 30 min into the bike segment (180 ml). Blood samples were collected and analyzed for CK, lactic acid (LA) and glucose (GL). Heart rate (HR), VO2, and RPE were measured.

Results: The 90kJ TT was enhanced by an average of 27 sec for 7 of the 10 subjects in the CP group. However, an ANOVA revealed no statistical difference for the time trial between the two groups (CP=395 +90 sec; CE=409 +78 sec). GL was statistically increased in the CP group. No differences were observed for LA, HR, VO2, or RPE. In the CP group there was a significant reduction of 36% for the 24-hour post exercise CK level.

Conclusions: These results suggest that CP, by providing additional CHO and amino acids, may reduce post-exercise muscle stress, as evidenced by a 36% decrease in 24- hour CK levels. A possible mechanism for this reduced stress could be through the maintenance of cell membrane integrity.

3.Effects 0f Post Exercise Carbohydrate-Protein Supplement On Skeletal Muscle Glycogen Storage

D.L. Fogt, J.L. Ivy Department of Kinesiology University of Texas, Austin, TX 78712 Previously it was shown that ingestion of a high carbohydrate-protein (CHO-PRO) supplement after glycogen-depleting exercise enabled a 55% greater time to exhaustion in a subsequent exercise bout when compared with a typical 6% carbohydrate (CHO) sports drink (Williams, M.B. et al., MSSE 31:(Suppl.) S124, 1999). It was hypothesized that the greater recovery following the CHO-PRO supplement was due to a greater rate of muscle glycogen storage. The present study was designed to investigate the effects of post exercise CHO-PRO and CHO supplements on muscle glycogen restoration. Eight endurance-trained (cycle VO2max = 62.1 ? 2.2 ml ? kg body wt-1 ? min-1) cyclists performed two trials consisting of a 2 h glycogen depletion ride followed by ingestion of 12 oz of CHO-PRO or CHO supplement immediately and 2 h post exercise. Trials were randomized and separated by 7 days. The manufacturer-suggested serving (12 oz) of the CHO-PRO contained 53 g CHO and 14 g PRO, providing 0.8 g CHO ? kg body wt-1 and 0.2 g PRO ? kg body wt-1, whereas the equivalent serving (12 oz) of the CHO supplement provided 20 g CHO (0.3 g CHO ? kg body wt-1) and contained no PRO. Blood samples were collected prior to exercise and throughout the 4 h post exercise recovery period. Muscle biopsies were taken immediately after and 4 h post exercise for determination of muscle glycogen content.

Results: Blood lactate concentrations were similar following both treatments. However, ingestion of the CHO-PRO supplement resulted in a 17% greater plasma glucose response [incremental area under the curve (AUC)], a 92% greater insulin response (AUC) and a 128% greater storage of muscle glycogen (33.66 ? 4.5 and 17.42 ? 5.2 ?mol ? g dry weight-1 ? h-1 for CHO-PRO and CHO, respectively) compared to the CHO supplement (p< 0.05).

Conclusions: Thus, the greater rate of recovery following glycogen-depleting exercise during the CHO-PRO treatment shown previously was likely due to a greater glycogen restoration although other possibilities exist.

Frequently Asked Questions

What results can I expect with Endurox R4?
In studies against the leading sports drink, Endurox R4 delivered equal hydration effectiveness and was proven to:

Enhance performance and extend endurance by 55%
Decrease post-exercise muscle damage by 36%
Reduce free radical build-up by 69%, thereby protecting against muscle stress and soreness
Increase muscle glycogen replenishment by 220%
Increase insulin levels by 70%, thereby speeding the replenishment of muscle glycogen stores and the rebuilding of protein

Why is insulin the "master recovery hormone"?

Insulin regulates glycogen replenishment post exercise and also maintains muscle protein by both preventing breakdown and stimulating rebuilding of protein. Because Endurox R4 maximizes insulin levels, it produces a faster and stronger recovery.

What is the importance of OR2 (Optimum Recovery Ratio)?
Although researchers have noted that protein can provide a number of essential benefits in the recovery process, too much protein can actually slow restoration of glycogen and rehydration. Endurox R4 is unique because it provides the ideal Optimum Recovery Ratio of 4:1 (4 grams of carbohydrate to one gram of protein) to deliver the benefits of protein without negatively affecting rehydration and glycogen restoration. Endurox R4 is so unique it has a patent.

How does ciwujia and glutamine help in the recovery process?
Standardized extract of ciwujia (Endurox) and glutamine have been shown to bolster the body's defense mechanisms, a key benefit for the training athlete, as well as to reduce stress during exercise.

Supplement Facts:

Serving Size: 2 Rounded Scoops (74.08g)
Servings Per Container: 14

Amount Per Serving:

Calories: 270
-Calories From Fat: 10
Total Fat: 1g 1%
-Saturated Fat: 0g
Cholesterol: 10mg 3%
Total Carbohydrate: 52g 18%
-Sugars: 40g
Protein: 13g 26%
Vitamin C: 470mg 780%
Vitamin E: 400 I.U. 1330%
Calcium: 100mg 10%
Magnesium: 240mg 65%
Sodium: 220mg 9%
Potassium: 120mg 3%
L-Glutamine: 2560mg
Branched Chain Amino Acids: 2719mg

Directions:
Endurox R4 should be taken within two hours after exercise. During this time your muscle cells are far more efficient in replenishing muscle glycogen stores when there is sufficient amount of carbohydrate available and insulin is stimulated. Endurox R4 provides the necessary carbohydrate and protein in the correct proportion to stimulate insulin, the body's master recovery hormone. The amount of Endurox R4 you should consume depends on your body weight. The table below offers a good guideline:

Body Weight - lbs:
120 lbs. 1-Scoop
160 lbs. 2-Scoops
190 lbs. 3-Scoops
220+ 4-Scoops

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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REVIEW SNAPSHOT®

by PowerReviews

Endurox R4, 2.28 Lbs.

3.0

(based on 1 review)

Reviewed by 1 customer

Displaying review 1

7/13/2010

3.0

Easy on the digestive system

By KtownTeach

from Kenosha, WI

Pros

Digestible
Nutritional
Tasty

Cons

Little Effect

Best Uses

Recovery

Comments about Endurox R4, 2.28 Lbs.:

Started using midseason for bike training. Seems to hold off muscle fatique post ride. I have a very touchy disgestive system. No problems with upper or lower digestive concerns. Good taste.

Displaying review 1

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